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Extensive DNA-binding specificity divergence of a conserved transcription regulator

The DNA sequence recognized by a transcription regulator can be conserved across large evolutionary distances. For example, it is known that many homologous regulators in yeasts and mammals can recognize the same (or closely related) DNA sequences. In contrast to this paradigm, we describe a case in...

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מידע ביבליוגרפי
Main Authors: Baker, Christopher R., Tuch, Brian B., Johnson, Alexander D.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088634/
https://ncbi.nlm.nih.gov/pubmed/21498688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019177108
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