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Extensive DNA-binding specificity divergence of a conserved transcription regulator
The DNA sequence recognized by a transcription regulator can be conserved across large evolutionary distances. For example, it is known that many homologous regulators in yeasts and mammals can recognize the same (or closely related) DNA sequences. In contrast to this paradigm, we describe a case in...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3088634/ https://ncbi.nlm.nih.gov/pubmed/21498688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019177108 |
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