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Conserved and species-specific transcription factor co-binding patterns drive divergent gene regulation in human and mouse

The mouse is widely used as system to study human genetic mechanisms. However, extensive rewiring of transcriptional regulatory networks often confounds translation of findings between human and mouse. Site-specific gain and loss of individual transcription factor binding sites (TFBS) has caused fun...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Diehl, Adam G, Boyle, Alan P
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829737/
https://ncbi.nlm.nih.gov/pubmed/29361190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky018
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