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Conserved and species-specific transcription factor co-binding patterns drive divergent gene regulation in human and mouse

The mouse is widely used as system to study human genetic mechanisms. However, extensive rewiring of transcriptional regulatory networks often confounds translation of findings between human and mouse. Site-specific gain and loss of individual transcription factor binding sites (TFBS) has caused fun...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Diehl, Adam G, Boyle, Alan P
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829737/
https://ncbi.nlm.nih.gov/pubmed/29361190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky018
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