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How transcription circuits explore alternative architectures while maintaining overall circuit output

Transcription regulators bind to cis-regulatory sequences and thereby control the expression of target genes. While transcription regulators and the target genes that they regulate are often deeply conserved across species, the connections between the two change extensively over evolutionary timesca...

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Publicat a:Genes Dev
Autors principals: Dalal, Chiraj K., Johnson, Alexander D.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588923/
https://ncbi.nlm.nih.gov/pubmed/28860157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.303362.117
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