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Hydride Transfer vs. Hydrogen Radical Transfer in Thymidylate Synthase
[Image: see text] The nature of an H-transfer in the thymidylate synthase catalyzed reaction was investigated by comparison of the wild-type enzyme with W80M mutant. The nature of the H-transfer was not affected, as indicated by intrinsic isotope effects and their temperature dependence. These findi...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253763/ https://ncbi.nlm.nih.gov/pubmed/16637621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja060196o |
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