Decrease in the production of beta-amyloid by berberine inhibition of the expression of beta-secretase in HEK293 cells

BACKGROUND: Berberine (BER), the major alkaloidal component of Rhizoma coptidis, has multiple pharmacological effects including inhibition of acetylcholinesterase, reduction of cholesterol and glucose levels, anti-inflammatory, neuroprotective and neurotrophic effects. It has also been demonstrated...

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Autori principali: Zhu, Feiqi, Wu, Fujun, Ma, Ying, Liu, Guangjian, Li, Zhong, Sun, Yong'an, Pei, Zhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253691/
https://ncbi.nlm.nih.gov/pubmed/22152059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-125
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