Radioimmunotargeting of Malignant Glioma by Monoclonal Antibody D2C7 Reactive Against Both Wild-Type and Variant III Mutant Epidermal Growth Factor Receptors

INTRODUCTION: Malignant glioma remains a significant therapeutic challenge and immunotherapeutics might be a beneficial approach for these patients. A monoclonal antibody (MAb) specific for multiple molecular targets could expand the treatable patient population and the fraction of tumor cells targe...

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Autori principali: Zalutsky, Michael R., Boskovitz, Abraham, Kuan, Chien-Tsun, Pegram, Charles N, Ayriss, Joanne, Wikstrand, Carol J, Buckley, Anne F., Lipp, Eric S., Herndon, James E., McLendon, Roger E., Bigner, Darell D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253233/
https://ncbi.nlm.nih.gov/pubmed/21958852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2011.06.005
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