Treatment of HER2 Positive Breast Carcinomatous Meningitis with Intrathecal Administration of α-Particle Emitting (211)At-labeled Trastuzumab

INTRODUCTION: Carcinomatous meningitis (CM) is a devastating disease characterized by the dissemination of malignant tumor cells into the subarachnoid space along the brain and spine. Systemic treatment with monoclonal antibody (mAb) trastuzumab can be effective against HER2-positive systemic breast...

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Bibliographic Details
Main Authors: Boskovitz, Abraham, McLendon, Roger E., Okamura, Tatsunori, Sampson, John H., Bigner, Darell D., Zalutsky, Michael R.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720883/
https://ncbi.nlm.nih.gov/pubmed/19647172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2009.04.003
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