Treatment of HER2 Positive Breast Carcinomatous Meningitis with Intrathecal Administration of α-Particle Emitting (211)At-labeled Trastuzumab

INTRODUCTION: Carcinomatous meningitis (CM) is a devastating disease characterized by the dissemination of malignant tumor cells into the subarachnoid space along the brain and spine. Systemic treatment with monoclonal antibody (mAb) trastuzumab can be effective against HER2-positive systemic breast...

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Detalhes bibliográficos
Main Authors: Boskovitz, Abraham, McLendon, Roger E., Okamura, Tatsunori, Sampson, John H., Bigner, Darell D., Zalutsky, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720883/
https://ncbi.nlm.nih.gov/pubmed/19647172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2009.04.003
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