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Antiparallel EmrE exports drugs by exchanging between asymmetric structures
Small multidrug resistance (SMR) transporters provide an ideal system to study the minimal requirements for active transport. EmrE is an E. coli SMR transporter that exports a broad class of polyaromatic cation substrates, thus conferring resistance to drug compounds matching this chemical descripti...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253143/ https://ncbi.nlm.nih.gov/pubmed/22178925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10703 |
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