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Blocking Dynamics of the SMR Transporter EmrE Impairs Efflux Activity

EmrE is a small multidrug resistance transporter that has been well studied as a model for secondary active transport. Because transport requires the protein to convert between at least two states open to opposite sides of the membrane, it is expected that blocking these conformational transitions w...

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Detalhes bibliográficos
Main Authors: Dutta, Supratik, Morrison, Emma A., Henzler-Wildman, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129506/
https://ncbi.nlm.nih.gov/pubmed/25099800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.030
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