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Transported Substrate Determines Exchange Rate in the Multidrug Resistance Transporter EmrE

EmrE, a small multidrug resistance transporter, serves as an ideal model to study coupling between multidrug recognition and protein function. EmrE has a single small binding pocket that must accommodate the full range of diverse substrates recognized by this transporter. We have studied a series of...

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Detalhes bibliográficos
Main Authors: Morrison, Emma A., Henzler-Wildman, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945343/
https://ncbi.nlm.nih.gov/pubmed/24448799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.535328
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