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Transported Substrate Determines Exchange Rate in the Multidrug Resistance Transporter EmrE
EmrE, a small multidrug resistance transporter, serves as an ideal model to study coupling between multidrug recognition and protein function. EmrE has a single small binding pocket that must accommodate the full range of diverse substrates recognized by this transporter. We have studied a series of...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945343/ https://ncbi.nlm.nih.gov/pubmed/24448799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.535328 |
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