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Identification of an Alternating-Access Dynamics Mutant of EmrE with Impaired Transport

Proteins that perform active transport must alternate the access of a binding site, first to one side of a membrane and then to the other, resulting in the transport of bound substrates across the membrane. To better understand this process, we sought to identify mutants of the small multidrug resis...

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Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Wu, Chao, Wynne, Samantha A., Thomas, Nathan E., Uhlemann, Eva-Maria, Tate, Christopher G., Henzler-Wildman, Katherine A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599891/
https://ncbi.nlm.nih.gov/pubmed/31158365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.05.035
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