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Kinetics of iron release from transferrin bound to the transferrin receptor at endosomal pH

BACKGROUND: Human serum transferrin (hTF) is a bilobal glycoprotein that reversibly binds Fe(3+) and delivers it to cells by the process of receptor-mediated endocytosis. Despite decades of research, the precise events resulting in iron release from each lobe of hTF within the endosome have not been...

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Bibliografische gegevens
Hoofdauteurs: Steere, Ashley N., Byrne, Shaina L., Chasteen, N. Dennis, Mason, Anne B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253137/
https://ncbi.nlm.nih.gov/pubmed/21699959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2011.06.003
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