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Identification of a Kinetically Significant Anion Binding (KISAB) Site in the N-Lobe of Human Serum Transferrin()

Human serum transferrin (hTF) binds two ferric iron ions which are delivered to cells in a transferrin receptor (TFR) mediated process. Critical to the delivery of iron to cells is the binding of hTF to the TFR and the efficient release of iron orchestrated by the interaction. Within the endosome, i...

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Autores principales: Byrne, Shaina L., Steere, Ashley N., Chasteen, N. Dennis, Mason, Anne B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197725/
https://ncbi.nlm.nih.gov/pubmed/20397659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1003519
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