A Mutation in Intracellular Loop 4 Affects the Drug-Efflux Activity of the Yeast Multidrug Resistance ABC Transporter Pdr5p

Multidrug resistance protein Pdr5p is a yeast ATP-binding cassette (ABC) transporter in the plasma membrane. It confers multidrug resistance by active efflux of intracellular drugs. However, the highly polymorphic Pdr5p from clinical strain YJM789 loses its ability to expel azole and cyclohexmide. T...

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Detaylı Bibliyografya
Asıl Yazarlar: Guo, Xiaoxian, Li, Jingkai, Wang, Tanjun, Liu, Zhenhua, Chen, Xin, Li, Yudong, Gu, Zhenglong, Mao, Xuming, Guan, Wenjun, Li, Yongquan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253106/
https://ncbi.nlm.nih.gov/pubmed/22238618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029520
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