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Antagonistic Changes in Sensitivity to Antifungal Drugs by Mutations of an Important ABC Transporter Gene in a Fungal Pathogen

Fungal pathogens can be lethal, especially among immunocompromised populations, such as patients with AIDS and recipients of tissue transplantation or chemotherapy. Prolonged usage of antifungal reagents can lead to drug resistance and treatment failure. Understanding mechanisms that underlie drug r...

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Detalhes bibliográficos
Main Authors: Guan, Wenjun, Jiang, Huifeng, Guo, Xiaoxian, Mancera, Eugenio, Xu, Lin, Li, Yudong, Steinmetz, Lars, Li, Yongquan, Gu, Zhenglong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892482/
https://ncbi.nlm.nih.gov/pubmed/20593017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011309
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