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Antagonistic Changes in Sensitivity to Antifungal Drugs by Mutations of an Important ABC Transporter Gene in a Fungal Pathogen

Fungal pathogens can be lethal, especially among immunocompromised populations, such as patients with AIDS and recipients of tissue transplantation or chemotherapy. Prolonged usage of antifungal reagents can lead to drug resistance and treatment failure. Understanding mechanisms that underlie drug r...

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Autors principals: Guan, Wenjun, Jiang, Huifeng, Guo, Xiaoxian, Mancera, Eugenio, Xu, Lin, Li, Yudong, Steinmetz, Lars, Li, Yongquan, Gu, Zhenglong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892482/
https://ncbi.nlm.nih.gov/pubmed/20593017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011309
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