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Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival
The receptor-like tyrosine phosphatase CD45 positively regulates antigen receptor signaling by dephosphorylating the inhibitory tyrosine of the src family kinases. CD45-deficient mice fail to fully unmask the role of CD45 in B cells because of the expression of a partially redundant tyrosine phospha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252956/ https://ncbi.nlm.nih.gov/pubmed/22135465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117374108 |
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