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Structural basis of coactivation of liver receptor homolog-1 by β-catenin
We report the three-dimensional structure of a β-catenin armadillo repeat in complex with the liver receptor homolog-1 (LRH-1) ligand binding domain at 2.8 Å resolution as the first structure of β-catenin in complex with any nuclear receptor. The surface of β-catenin that binds LRH-1 partly overlaps...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252924/ https://ncbi.nlm.nih.gov/pubmed/22187462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117036108 |
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