The FKBP52 Cochaperone Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling

FKBP52 and β-catenin have emerged in recent years as attractive targets for prostate cancer treatment. β-catenin interacts directly with the androgen receptor (AR) and has been characterized as a co-activator of AR-mediated transcription. FKBP52 is a positive regulator of AR in cellular and whole an...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Storer Samaniego, Cheryl, Suh, Ji Ho, Chattopadhyay, Arundhati, Olivares, Karen, Guy, Naihsuan, Sivils, Jeffrey C., Dey, Prasenjit, Yumoto, Fumiaki, Fletterick, Robert J., Strom, Anders M., Gustafsson, Jan-Åke, Webb, Paul, Cox, Marc B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514735/
https://ncbi.nlm.nih.gov/pubmed/26207810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134015
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