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Genetic code translation displays a linear trade-off between efficiency and accuracy of tRNA selection
Rapid and accurate translation of the genetic code into protein is fundamental to life. Yet due to lack of a suitable assay, little is known about the accuracy-determining parameters and their correlation with translational speed. Here, we develop such an assay, based on Mg(2+) concentration changes...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252910/ https://ncbi.nlm.nih.gov/pubmed/22190491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116480109 |
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