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Structure-based design of conformation- and sequence-specific antibodies against amyloid β
Conformation-specific antibodies that recognize aggregated proteins associated with several conformational disorders (e.g., Parkinson and prion diseases) are invaluable for diagnostic and therapeutic applications. However, no systematic strategy exists for generating conformation-specific antibodies...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252897/ https://ncbi.nlm.nih.gov/pubmed/22171009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111232108 |
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