Lymphoid Tissue Damage in HIV-1 Infection Depletes Naïve T Cells and Limits T Cell Reconstitution after Antiretroviral Therapy

Highly active antiretroviral therapy (HAART) can suppress HIV-1 replication and normalize the chronic immune activation associated with infection, but restoration of naïve CD4(+) T cell populations is slow and usually incomplete for reasons that have yet to be determined. We tested the hypothesis th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zeng, Ming, Southern, Peter J., Reilly, Cavan S., Beilman, Greg J., Chipman, Jeffrey G., Schacker, Timothy W., Haase, Ashley T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252371/
https://ncbi.nlm.nih.gov/pubmed/22241988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002437
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