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The Role of Collagen Deposition in Depleting CD4+ T Cells and Limiting Reconstitution in HIV-1 and SIV Infections through Damage to the Secondary Lymphoid Organ Niche
The hallmark of HIV/SIV infections is the progressive depletion of CD4+ T cells that ultimately renders the host incapable of defending against AIDS defining opportunistic infections and malignancies. Although many potential mechanisms have been proposed to explain CD4+ T cell loss, we review here t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650387/ https://ncbi.nlm.nih.gov/pubmed/18595731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2008.04.002 |
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