Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

The hallmark of HIV-1 and SIV infections is CD4(+) T cell depletion. Both direct cell killing and indirect mechanisms related to immune activation have been suggested to cause the depletion of T cells. We have now identified a mechanism by which immune activation-induced fibrosis of lymphoid tissues...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zeng, Ming, Smith, Anthony J., Wietgrefe, Stephen W., Southern, Peter J., Schacker, Timothy W., Reilly, Cavan S., Estes, Jacob D., Burton, Gregory F., Silvestri, Guido, Lifson, Jeffrey D., Carlis, John V., Haase, Ashley T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2011
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049394/
https://ncbi.nlm.nih.gov/pubmed/21393864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45157
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