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Structure-based redesign of an edema toxin inhibitor
Edema Factor toxin (EF) of Bacillus anthracis (NIAID category A), and several other toxins from NIAID category B Biodefense target bacteria are adenylyl cyclases or adenylyl cyclase agonists that catalyze the conversion of ATP to 3′,5′-cyclic adenosine monophosphate (cAMP). We previously identified...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251925/ https://ncbi.nlm.nih.gov/pubmed/22154558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.10.091 |
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