Testing the Efficacy and Toxicity of Adenylyl Cyclase Inhibitors against Enteric Pathogens Using In Vitro and In Vivo Models of Infection

Enterotoxigenic Escherichia coli (ETEC) produces the ADP-ribosyltransferase toxin known as heat-labile enterotoxin (LT). In addition to the toxic effect of LT resulting in increases of cyclic AMP (cAMP) and disturbance of cellular metabolic processes, this toxin promotes bacterial adherence to intes...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Moen, Scott T., Blumentritt, Carla A., Slater, Terry M., Patel, Shilpa D., Tutt, Christopher B., Estrella-Jimenez, Maria E., Pawlik, Jennifer, Sower, Laurie, Popov, Vsevolod L., Schein, Catherine H., Gilbertson, Scott R., Peterson, Johnny W., Torres, Alfredo G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2010
Предметы:
Host Response and Inflammation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849411/
https://ncbi.nlm.nih.gov/pubmed/20123712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01114-09
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы