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Intradermal Electroporation of Naked Replicon RNA Elicits Strong Immune Responses

RNA-based vaccines represent an interesting immunization modality, but suffer from poor stability and a lack of efficient and clinically feasible delivery technologies. This study evaluates the immunogenic potential of naked in vitro transcribed Semliki Forest virus replicon RNA (RREP) delivered int...

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Detalhes bibliográficos
Main Authors: Johansson, Daniel X., Ljungberg, Karl, Kakoulidou, Maria, Liljeström, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251598/
https://ncbi.nlm.nih.gov/pubmed/22238645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029732
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