Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma

Dickkopf-1 (DKK1), broadly expressed in myeloma cells but highly restricted in normal tissues, together with its functional roles as an osteoblast formation inhibitor, may be an ideal target for immunotherapy in myeloma. Our previous studies have shown that DKK1 (peptide)–specific CTLs can effective...

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Bibliografiska uppgifter
Huvudupphovsmän: Qian, Jianfei, Zheng, Yuhuan, Zheng, Chengyun, Wang, Lijuan, Qin, Hong, Hong, Sungyoul, Li, Haiyan, Lu, Yong, He, Jin, Yang, Jing, Neelapu, Sattva, Kwak, Larry W., Hou, Jian, Yi, Qing
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2012
Ämnen:
Immunobiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251227/
https://ncbi.nlm.nih.gov/pubmed/22049519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-368472
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