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Roles of Idiotype-Specific T Cells in Myeloma Cell Growth and Survival: Th1 and CTL Cells Are Tumoricidal While Th2 Cells Promote Tumor Growth
Idiotype protein (Id) secreted by myeloma cells is a tumor-specific antigen. Id-based immunotherapy has been explored in patients with myeloma, and results are disappointing. Although previous studies have demonstrated that Id-specific CTLs are able to lyse myeloma cells, it is unclear whether other...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575640/ https://ncbi.nlm.nih.gov/pubmed/18922919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2213 |
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