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Optimizing immunotherapy in multiple myeloma: restoring the function of patients' monocyte-derived dendritic cells by inhibiting p38 or activating MEK/ERK MAPK and neutralizing interleukin-6 in progenitor cells

Previous studies demonstrated that circulating dendritic cells (DCs) in myeloma patients were functionally abnormal. However, the phenotype and function of patients' monocyte-derived DCs (MoDCs), which are commonly used for immunotherapy, were poorly defined. This study was undertaken to examin...

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Hlavní autoři: Wang, Siqing, Hong, Sungyoul, Yang, Jing, Qian, Jianfei, Zhang, Xiang, Shpall, Elizabeth, Kwak, Larry W., Yi, Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Hematology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895445/
https://ncbi.nlm.nih.gov/pubmed/16917008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-016980
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