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Tumor evasion of the immune system: inhibiting p38 MAPK signaling restores the function of dendritic cells in multiple myeloma

Dendritic cells (DCs) from patients with cancer are functionally defective, but the molecular mechanisms underlying these defects are poorly understood. In this study, we used the murine 5TGM1 myeloma model to examine the effects and mechanisms of tumor-derived factors on the differentiation and fun...

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Autors principals: Wang, Siqing, Yang, Jing, Qian, Jianfei, Wezeman, Michele, Kwak, Larry W., Yi, Qing
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Hematology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895733/
https://ncbi.nlm.nih.gov/pubmed/16291589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2486
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