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Cross talk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4(+) and CD8(+) T cells
The bone and immune systems are closely related through cellular and molecular interactions. Because bone-resorbing osteoclasts (OCs) are derived from the monocyte/macrophage lineage, similar to dendritic cells (DCs), we hypothesized that OCs could serve as antigen-presenting cells (APCs) to activat...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910608/ https://ncbi.nlm.nih.gov/pubmed/20304810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-255026 |
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