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Computational design of a symmetric homodimer using β-strand assembly
Computational design of novel protein–protein interfaces is a test of our understanding of protein interactions and has the potential to allow modification of cellular physiology. Methods for designing high-affinity interactions that adopt a predetermined binding mode have proved elusive, suggesting...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251150/ https://ncbi.nlm.nih.gov/pubmed/22143762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115124108 |
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