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Structural insights into protein arginine symmetric dimethylation by PRMT5
Symmetric and asymmetric dimethylation of arginine are isomeric protein posttranslational modifications with distinct biological effects, evidenced by the methylation of arginine 3 of histone H4 (H4R3): symmetric dimethylation of H4R3 leads to repression of gene expression, while asymmetric dimethyl...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251124/ https://ncbi.nlm.nih.gov/pubmed/22143770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106946108 |
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