Structural insights into protein arginine symmetric dimethylation by PRMT5

Symmetric and asymmetric dimethylation of arginine are isomeric protein posttranslational modifications with distinct biological effects, evidenced by the methylation of arginine 3 of histone H4 (H4R3): symmetric dimethylation of H4R3 leads to repression of gene expression, while asymmetric dimethyl...

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Detalles Bibliográficos
Autores principales: Sun, Litao, Wang, Mingzhu, Lv, Zongyang, Yang, Na, Liu, Yingfang, Bao, Shilai, Gong, Weimin, Xu, Rui-Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251124/
https://ncbi.nlm.nih.gov/pubmed/22143770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106946108
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