RNA–protein binding interface in the telomerase ribonucleoprotein

Telomerase is a specialized reverse transcriptase containing an intrinsic telomerase RNA (TR) which provides the template for telomeric DNA synthesis. Distinct from conventional reverse transcriptases, telomerase has evolved a unique TR-binding domain (TRBD) in the catalytic telomerase reverse trans...

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Hlavní autoři: Bley, Christopher J., Qi, Xiaodong, Rand, Dustin P., Borges, Chad R., Nelson, Randall W., Chen, Julian J.-L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
Telomerase and Retrotransposons: Reverse Transcriptases That Shaped Genomes Special Feature Sackler Colloquium
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251108/
https://ncbi.nlm.nih.gov/pubmed/22123986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100270108
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