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Functional importance of telomerase pseudoknot revealed by single-molecule analysis

Telomerase ribonucleoprotein (RNP) employs an RNA subunit to template the addition of telomeric repeats onto chromosome ends. Previous studies have suggested that a region of the RNA downstream of the template may be important for telomerase activity and that the region could fold into a pseudoknot....

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Autori principali: Mihalusova, Mariana, Wu, John Y., Zhuang, Xiaowei
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251044/
https://ncbi.nlm.nih.gov/pubmed/21571642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017686108
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