Protection from Myocardial Ischemia/Reperfusion Injury by a Positive Allosteric Modulator of the A(3) Adenosine Receptor

Adenosine is increased in ischemic tissues where it serves a protective role by activating adenosine receptors (ARs), including the A(3) AR subtype. We investigated the effect of N-{2-[(3,4-dichlorophenyl)amino]quinolin-4-yl}cyclohexanecarboxamide (LUF6096), a positive allosteric modulator of the A(...

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Detalhes bibliográficos
Main Authors: Du, Lili, Gao, Zhan-Guo, Nithipatikom, Kasem, IJzerman, Adriaan P., van Veldhoven, Jacobus P. D., Jacobson, Kenneth A., Gross, Garrett J., Auchampach, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Drug Discovery and Translational Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251031/
https://ncbi.nlm.nih.gov/pubmed/22011434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.187559
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