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Age-dependent alteration of TGF-β signalling in osteoarthritis
Osteoarthritis (OA) is a disease of articular cartilage, with aging as the main risk factor. In OA, changes in chondrocytes lead to the autolytic destruction of cartilage. Transforming growth factor-β has recently been demonstrated to signal not only via activin receptor-like kinase 5 (ALK5)-induced...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer-Verlag
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250613/ https://ncbi.nlm.nih.gov/pubmed/21638205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-011-1194-6 |
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