Impaired CK1 Delta Activity Attenuates SV40-Induced Cellular Transformation In Vitro and Mouse Mammary Carcinogenesis In Vivo

Simian virus 40 (SV40) is a powerful tool to study cellular transformation in vitro, as well as tumor development and progression in vivo. Various cellular kinases, among them members of the CK1 family, play an important role in modulating the transforming activity of SV40, including the transformin...

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Main Authors: Hirner, Heidrun, Günes, Cagatay, Bischof, Joachim, Wolff, Sonja, Grothey, Arnhild, Kühl, Marion, Oswald, Franz, Wegwitz, Florian, Bösl, Michael R., Trauzold, Anna, Henne-Bruns, Doris, Peifer, Christian, Leithäuser, Frank, Deppert, Wolfgang, Knippschild, Uwe
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250488/
https://ncbi.nlm.nih.gov/pubmed/22235331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029709
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