Newly Developed CK1-Specific Inhibitors Show Specifically Stronger Effects on CK1 Mutants and Colon Cancer Cell Lines

Protein kinases of the CK1 family can be involved in numerous physiological and pathophysiological processes. Dysregulated expression and/or activity as well as mutation of CK1 isoforms have previously been linked to tumorigenesis. Among all neoplastic diseases, colon and rectal cancer (CRC) represe...

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Publicado en:Int J Mol Sci
Main Authors: Liu, Congxing, Witt, Lydia, Ianes, Chiara, Bischof, Joachim, Bammert, Marie-Thérèse, Baier, Joana, Kirschner, Stefan, Henne-Bruns, Doris, Xu, Pengfei, Kornmann, Marko, Peifer, Christian, Knippschild, Uwe
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941124/
https://ncbi.nlm.nih.gov/pubmed/31817920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246184
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