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Newly Developed CK1-Specific Inhibitors Show Specifically Stronger Effects on CK1 Mutants and Colon Cancer Cell Lines

Protein kinases of the CK1 family can be involved in numerous physiological and pathophysiological processes. Dysregulated expression and/or activity as well as mutation of CK1 isoforms have previously been linked to tumorigenesis. Among all neoplastic diseases, colon and rectal cancer (CRC) represe...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Liu, Congxing, Witt, Lydia, Ianes, Chiara, Bischof, Joachim, Bammert, Marie-Thérèse, Baier, Joana, Kirschner, Stefan, Henne-Bruns, Doris, Xu, Pengfei, Kornmann, Marko, Peifer, Christian, Knippschild, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941124/
https://ncbi.nlm.nih.gov/pubmed/31817920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246184
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