Microtubules Depolymerization Caused by the CK1 Inhibitor IC261 May Be Not Mediated by CK1 Blockage

The ubiquitously expressed serine/threonine specific casein kinase 1 (CK1) family plays important roles in the regulation of various physiological processes. Small-molecule inhibitors, such as the CK1δ/ε selectively inhibitor IC261, have been used to antagonize CK1 phosphorylation events in cells in...

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Main Authors: Stöter, Martin, Krüger, Marc, Banting, George, Henne-Bruns, Doris, Knippschild, Uwe
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061085/
https://ncbi.nlm.nih.gov/pubmed/24937750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100090
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