TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild-type and TRPC1(−/−) mice

Ca(2+)-permeable cation channels consisting of canonical transient receptor potential 1 (TRPC1) proteins mediate Ca(2+) influx pathways in vascular smooth muscle cells (VSMCs), which regulate physiological and pathological functions. We investigated properties conferred by TRPC1 proteins to native s...

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Bibliographic Details
Main Authors: Shi, Jian, Ju, Min, Abramowitz, Joel, Large, William A., Birnbaumer, Lutz, Albert, Anthony P.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2012
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250247/
https://ncbi.nlm.nih.gov/pubmed/21968068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-185611
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