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Orai proteins interact with TRPC channels and confer responsiveness to store depletion

The TRPC (C-type transient receptor potential) class of ion channels has been hypothesized to participate in store-operated Ca(2+) entry (SOCE). Recently, however, STIM1 and Orai1 proteins have been proposed to form SOCE channels. Whether TRPCs participate in SOCE that is dependent on or regulated b...

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Detalhes bibliográficos
Main Authors: Liao, Yanhong, Erxleben, Christian, Yildirim, Eda, Abramowitz, Joel, Armstrong, David L., Birnbaumer, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838661/
https://ncbi.nlm.nih.gov/pubmed/17360584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611692104
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