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Store‐operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells

KEY POINTS: Depletion of Ca(2+) stores activates store‐operated channels (SOCs), which mediate Ca(2+) entry pathways that regulate cellular processes such as contraction, proliferation and gene expression. In vascular smooth muscle cells (VSMCs), stimulation of SOCs composed of canonical transient r...

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Bibliografske podrobnosti
izdano v:J Physiol
Main Authors: Shi, Jian, Miralles, Francesc, Birnbaumer, Lutz, Large, William A., Albert, Anthony P.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309361/
https://ncbi.nlm.nih.gov/pubmed/27753095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273302
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