T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling

Although transcriptional programs associated with T-cell specification and commitment have been described, the functional hierarchy and the roles of key regulators in structuring/orchestrating these programs remain unclear. Activation of Notch signaling in uncommitted precursors by the thymic stroma...

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Detalhes bibliográficos
Main Authors: Germar, Kristine, Dose, Marei, Konstantinou, Tassos, Zhang, Jiangwen, Wang, Hongfang, Lobry, Camille, Arnett, Kelly L., Blacklow, Stephen C., Aifantis, Iannis, Aster, Jon C., Gounari, Fotini
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250146/
https://ncbi.nlm.nih.gov/pubmed/22109558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110230108
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