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Notch signaling: switching an oncogene to a tumor suppressor
The Notch signaling pathway is a regulator of self-renewal and differentiation in several tissues and cell types. Notch is a binary cell-fate determinant, and its hyperactivation has been implicated as oncogenic in several cancers including breast cancer and T-cell acute lymphoblastic leukemia (T-AL...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3990910/ https://ncbi.nlm.nih.gov/pubmed/24608975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-355818 |
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