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Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think
Notch signaling is often considered a model hematopoietic proto-oncogene because of its role as the main trigger of T cell acute lymphoblastic leukemia (T-ALL). Although its role in T-ALL is well characterized and further supported by a high frequency of activating NOTCH1 mutations in T-ALL patients...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Rockefeller University Press
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182047/ https://ncbi.nlm.nih.gov/pubmed/21948802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111855 |
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