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Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think

Notch signaling is often considered a model hematopoietic proto-oncogene because of its role as the main trigger of T cell acute lymphoblastic leukemia (T-ALL). Although its role in T-ALL is well characterized and further supported by a high frequency of activating NOTCH1 mutations in T-ALL patients...

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Detalhes bibliográficos
Main Authors: Lobry, Camille, Oh, Philmo, Aifantis, Iannis
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182047/
https://ncbi.nlm.nih.gov/pubmed/21948802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111855
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