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Meiotic double-strand breaks occur once per pair of (sister) chromatids and, via Mec1/ATR and Tel1/ATM, once per quartet of chromatids
Meiotic recombination initiates via programmed double-strand breaks (DSBs). We investigate whether, at a given initiation site, DSBs occur independently among the four available chromatids. For a single DSB “hot spot”, the proportions of nuclei exhibiting zero, one, or two (or more) observable event...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250133/ https://ncbi.nlm.nih.gov/pubmed/22123968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117937108 |
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