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Increased Numbers of Nonattached Osteoclasts After Long-Term Zoledronic Acid Therapy in Mice

Osteoclasts are key players in the maintenance of bone, which is an endocrine target and organ. Bisphosphonates, used for the management of metastatic bone diseases and osteoporosis, suppress osteoclasts. However, the impact of continuously suppressed osteoclasts is unknown. In this study, mice rece...

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Bibliografske podrobnosti
Main Authors: Kuroshima, Shinichiro, Go, Virginia-Arlene A., Yamashita, Junro
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249684/
https://ncbi.nlm.nih.gov/pubmed/22109892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1439
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